Common Causes of Infertility in Women and How to Manage Them

Dr. Umme Ruman
Reviewed by Dr. Umme Ruman ,
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This information has been reviewed and approved by an experienced fertility specialist at Indira IVF to provide accurate and up-to-date guidance for our readers.

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Last updated: July 22, 2025

Synopsis

Infertility can be an emotionally exhausting experience, often filled with confusion, frustration, and questions that seem to have no clear answers. For women, the road to understanding fertility can be complex, involving a mix of hormonal, physical, emotional, and lifestyle factors.This guide explores the major reasons why women struggle to conceive, how these issues are diagnosed, and the effective strategies that exist for managing them. Most importantly, it reminds you that you’re not alone and that support, treatment, and hope are very much within reach.

 

Introduction to Infertility in Women

If you are a woman who has not been able to conceive even after a year of unprotected intercourse, you might be suffering from infertility issues. In case you are over the age of 35, then six months is the limit. Now, there are several causes of infertility in women​, including physiological and hormonal issues.

It is important to note that not being able to conceive doesn’t always mean that you are infertile. However, if this is accompanied by irregular or missed periods, repeated miscarriages, or painful menstruation or intercourse, you might have a fertility problem.

Since fertility declines with age, it is important to get prompt medical attention. Early diagnosis can make a huge difference and give you a better chance of success.

1. Ovulation Disorders

What It Is

Ovulation happens when the egg is released from your ovary. It is a monthly occurrence. However, when this doesn’t happen or it happens irregularly, it can cause ovulation disorders and make conception difficult.

Common Conditions

  • Polycystic Ovary Syndrome (PCOS) : A condition that causes ovarian cysts, irregular cycles, and hormonal imbalance.
  • Hypothalamic Dysfunction : Extreme weight loss, over-training, and stress can trigger this.
  • Thyroid Problems : Thyroid problems like hypothyroidism and hyperthyroidism can affect your ovulation.

How to Manage

  • The first thing you need to do is manage your stress and maintain a healthy weight. Being underweight or overweight can both cause problems.
  • Your doctor might prescribe medications that stimulate ovulation.
  • In some cases, your doctor might suggest hormone therapy to fix your hormone imbalance.

2. Fallopian Tube Blockage or Damage

What It Is

After the egg is released from the ovary, it is carried to the uterus through the fallopian tubes. If there is any damage or blockage, then it can stop conception.

Common Causes

  • Pelvic Inflammatory Disease (PID): STIs like gonorrhoea and chlamydia can cause damage to your fallopian tubes.
  • Endometriosis: The tissue growth from endometriosis can block your fallopian tubes.
  • Ectopic pregnancy: If you had an ectopic pregnancy before, your tubes might end up scarred or damaged.

How to Manage

  • The most common treatment is surgery that clears the blockage or repairs the fallopian tubes.
  • IVF (In vitro fertilisation): If you choose this route, you won’t have to worry about damaged fallopian tubes.

3. Endometriosis

What It Is

Endometriosis is a condition that occurs when tissue similar to the uterine lining starts growing outside the uterus. It can affect not just your ovaries and fallopian tubes, but your pelvic cavity as well.

Symptoms

  • Difficulty in conceiving
  • Painful menstrual cramps
  • Pain during intercourse
  • Chronic pelvic pain

How to Manage

  • You can manage the pain caused by endometriosis using NSAIDs.
  • Hormonal therapies like GnRH agonists or birth control pills can help as well.
  • If nothing works, laparoscopic surgery is performed to remove the endometrial tissue.

4. Uterine or Cervical Problems

What It Is

Structural issues in the uterus or cervix can affect implantation or hinder sperm movement.

Types

Condition Impact on Fertility
Fibroids May distort the uterine lining or block the fallopian tubes
Polyps Prevent implantation
Cervical Stenosis Narrows the cervical opening
Uterine abnormalities Can interfere with embryo implantation

How to Manage

  • Hysteroscopic surgery for fibroids or polyps
  • Hormonal treatment to regulate cycles
  • Fertility procedures like IUI or IVF

5. Age-Related Fertility Decline

What It Is

Fertility in women begins to decline in their early 30s, with a more significant drop after 35 due to a decrease in egg quantity and quality.

Challenges

  • Harder to conceive naturally
  • Higher risk of miscarriage or chromosomal issues
  • Reduced effectiveness of fertility treatments

How to Manage

  • Consider early family planning
  • Egg freezing (ideally before 35)
  • IVF with own or donor eggs

6. Lifestyle and Environmental Factors

What It Is

Day-to-day choices and environmental exposure can significantly affect reproductive health.

Examples

  • Smoking: It damages eggs and reproductive organs
  • Alcohol: It can disrupt hormonal balance
  • Obesity or underweight: It affects ovulation
  • Poor diet: It lacks essential fertility nutrients
  • Chronic stress: It may impair hormonal function
  • Environmental toxins: Chemicals, radiation, pesticides

How to Manage

  • Stop smoking and reduce alcohol
  • Eat a balanced, nutrient-rich diet
  • Maintain a healthy BMI
  • Practice yoga, meditation, or therapy to reduce stress
  • Limit exposure to harmful chemicals

7. Unexplained Infertility

What It Is

It is a case where no clear reason for infertility is found, even after thorough testing.

Possible Hidden Factors

  • Poor egg or sperm quality undetectable by standard tests
  • Subtle hormonal issues
  • Immune system problems

How to Manage

  • Lifestyle improvements
  • Fertility treatments like IUI or IVF
  • Monitoring and trying again with tailored strategies

Diagnosis and Tests for Female Infertility

A comprehensive evaluation includes:

  • Blood tests: To check hormone levels
  • Ovulation tracking: Through basal body temperature or kits
  • Ultrasound: To assess ovarian health and detect cysts or fibroids
  • HSG (Hysterosalpingography): X-ray of the uterus and fallopian tubes
  • Laparoscopy: Minimally invasive surgery to check for endometriosis
  • Semen analysis: To rule out male infertility factors

Treatment Options for Female Infertility

  • Medications : Medications prescribed by a gynaecologist or fertility specialist for PCOS.
  • Surgery : To remove fibroids, polyps, or repair fallopian tubes.
  • Assisted reproductive technologies :
    • IUI (Intrauterine Insemination) : Sperm is placed directly into the uterus.
    • IVF (In Vitro Fertilisation) : Fertilisation occurs outside the body.
    • ICSI (Intracytoplasmic Sperm Injection) : Injecting the sperm into the egg in a lab setting and then placing the fertilised egg in the uterus.

Emotional Impact and Coping Tips

Infertility can bring emotional strain, often causing:

  • Anxiety
  • Depression
  • Relationship tension

Coping Strategies

  • Support groups : Share stories and reduce isolation
  • Counselling : Professional help to process emotions
  • Mindfulness and self-care : Yoga, journaling, creative hobbies
  • Stay informed : Knowledge empowers better decision-making

Conclusion

Infertility in women can arise from various causes—some obvious, others hidden. Whether it's ovulation issues, blocked tubes, or age-related decline, the good news is that most causes of infertility in women​ have effective treatments. By seeking medical help early, making lifestyle changes, and exploring assisted reproductive options, many women can successfully overcome fertility challenges. The journey may be tough, but with the right support, hope is never out of reach.

Frequently Asked Questions

What is the most common cause of infertility in women?

Can lifestyle changes improve fertility?

When should I see a doctor for infertility?

Is IVF the only solution for female infertility?

Can stress alone cause infertility in women?

Meet Top Fertility Specialists in Bangladesh at Indira IVF

Dr. Umme Ruman

Chief Infertility Specialist, MBBS(DU), FCPS(Obstetrics and Gynaecology), Fellowship in Assisted reproduction

Dr. Umme Ruman is a BMDC-registered infertility specialist based in Dhaka. She holds advanced qualifications in assisted reproductive techniques, sexual and reproductive medicine. Dr. Ruman serves as a Chief Consultant at Indira IVF Dhaka, helping patients with personalised fertility care based on her vast experience and expertise. Her knowledge and compassion will support couples navigating reproductive health challenges and guide them effectively towards their parenthood dreams.

Dr. Rezwana Kabir

IVF specialist, MBBS (SSMC), MS (Obstetrics and Gynaecology), Fellowship in Assisted reproduction

Dr. Rezwana Kabir is a BMDC-registered specialist in obstetrics and gynaecology, and now a part of Indira IVF’s team of fertility specialists in Bangladesh. She combines medical proficiency with a patient-centric approach, offering tailored solutions to couples seeking fertility assistance. She is committed to helping individuals confidently navigate the journey to parenthood through ethical, empathetic, and evidence-based care.

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